Abstract Deep Learning (DL) is the Machine Learning (ML) technique enabling breakthroughs in several industrial, business, and scientific workflows. Modern AI is the 4th industrial revolution. The new NVIDIA’s Deep Learning platform is providing the computational power demanded by the recent advances in AI. The new Pascal architecture of GPUs was specially designed the High-Performance Computing workloads necessary to train a Deep Neural Network with a huge amount of training data. The latest version of the CUDA language (version 8), and NVIDIA SDKs were improved to include specialized and highly optimized algorithm to extract GPUs full potential in DNN training and inference tasks. Large variety of training data can be efficiently used for training including text, audio, images, and video. This new computing model is delivering outstanding results in Computer Vision, Natural Language Processing, Language Translation, Speech Recognition, Recommendation Systems, Logistics, and Autonomous Cars and other Autonomous Machines.